منابع مشابه
[Myocardial dysfunction in sepsis].
Myocardial dysfunction appears in 25% of patients with severe sepsis and in 50% of patients with septic shock, even in the presence of hyper dynamic states. It is characterized by a reduction in left ventricle ejection fraction, that reverts at the seventh to tenth day of evolution. Right ventricular dysfunction and diastolic left ventricular dysfunction can also appear. There is no consensus i...
متن کاملSepsis-induced myocardial dysfunction: pathophysiology and management
Sepsis is aggravated by an inappropriate immune response to invading microorganisms, which occasionally leads to multiple organ failure. Several lines of evidence suggest that the ventricular myocardium is depressed during sepsis with features of diastolic dysfunction. Potential candidates responsible for septic cardiomyopathy include pathogen-associated molecular patterns (PAMPs), cytokines, a...
متن کاملSepsis and Myocardial Dysfunction: A Mini Review
Sepsis is the leading cause of mortality and a major healthcare concern worldwide [1]. It is characterized as a life-threatening disease, enhanced by a dysregulated immune host response to a precipitating infection. It’s a multifaceted disease, encompassing various organs and may lead to endorgan failure, shock and death. In a healthy human being the pro-inflammatory response triggered by micro...
متن کاملPathophysiology of sepsis-induced myocardial dysfunction
Sepsis-induced myocardial dysfunction is a common complication in septic patients and is associated with increased mortality. In the clinical setting, it was once believed that myocardial dysfunction was not a major pathological process in the septic patients, at least in part, due to the unavailability of suitable clinical markers to assess intrinsic myocardial function during sepsis. Although...
متن کاملMyocardial Dysfunction in Sepsis: A Large, Unsolved Puzzle
Sepsis has high incidence and mortality rates around the world. The role of cardiac depression in myocardial dysfunction during sepsis remains to be elucidated. This review attempts to summarize our understanding of the anatomical, histopathological, and pathophysiological mechanisms behind cardiac dysfunction. Biomarkers to detect cardiac depression have been used to recognize developing probl...
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ژورنال
عنوان ژورنال: Journal of Pediatric Critical Care
سال: 2018
ISSN: 2349-6592
DOI: 10.21304/2018.0504.00409